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Ovarian hydatid cyst - systematic review of clinicopathological and immunohistochemical characteristics of an unusual entity Ludmila Lozneanu, Raluca Anca Balan, Simona Eliza Giusca, Irina-Draga Caruntu, Cornelia Amalinei, Adriana Grigoras Primary ovarian hydatid disease HD is a rare entity, produced by the larval stage of Echinococcus granulosus. HD commonly involves liver, lung, abdomen cavity, spleen and is unusually identified in pelvic organs.
Based on our knowledge, the paper reviews 27 literature reports of ovarian HD, diagnosed during the last 20 years, providing a valuable database. Patients ages ranged between years, the gross appearance was that of mm diameter hydatid cysts HCs According to these reports, ovarian HD has non-specific clinical manifestations, such as abdominal or pelvic pain, nausea, dysmenorrhea or amenorrhea.
Ovarian HC microscopic pattern is characterized by three layers: pericyst or adventitia host origingerminal layer endocystand laminated membrane ectocyst. The immunoreaction triggered by parasites is initially rich in macrophages hpv vaccine side effects denmark neutrophils, followed by eosinophils hpv high risk c 02 positive lymphocytes, with numerous cluster of differentiation 8 CD8 -positive T-cells in active lesions and progressive forms.
In conclusion, the ovarian location of HD should be considered in any differential diagnosis of a cystic lesion, while it does not exclude synchronous ovarian tumors.
These cases reinforce the necessity of better measures of prophylaxis and screening of HD in endemic areas. The most common entities are gliomas, craniopharyngiomas and embryonal tumors, including primitive neuroectodermal tumors of the CNS, such as medulloblastoma.
Proper management of malignancies requires a histological diagnosis, especially in childhood, since diagnostic errors have a significant negative influence on the treatment and subsequently on the patient s care.
Experimental research conducted in the last years regarding the genomic and epigenetic landscape of pediatric brain tumors has provided considerable help in understanding their pathogenesis. New mutations and new signaling pathways have been associated with pediatric neoplasia, according to recent studies.
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Current therapeutic protocols recommend triple therapy, consisting in the surgical resection of the tumor, radiotherapy and chemotherapy. Although immunotherapy and gene therapy continue to be a challenge, extensive studies are needed in order to confirm their promising role in the management of pediatric brain tumors.
If incidence trends continue, the annual number of HPV-positive oropharyngeal cancers is expected to overcome the annual number of cervical cancers by the yearin the US. Aim: The aim of this paper is to review the recent data about several topics including risk factors of HPV-positive OPSCCs, guidelines in diagnostic evaluation, treatment, prognosis and prevention strategies, through prophylactic HPV vaccine on both sexes.
Nowadays, HPV detection is a clinical standard of care for oropharyngeal malignancy by reporting tumors as HPV positive or p16 positive.
The extremely rare concha of Zuckerkandl reviewed and reported Mugurel Constantin Rusu, Mihai Sandulescu, Carmen Aurelia Mogoanta, Adelina Maria Jianu Background: Usual descriptions indicate three or maximum four nasal turbinates conchae attached to the lateral nasal wall.
The middle, superior and, occasionally, supreme ones belong to the ethmoid bone.
Harper also authored many of the published, scholarly papers about the vaccines. She is now the latest in a long string of experts who are pressing the red alert button on the devastating consequences and irrelevancy of these vaccines. Harper made her surprising confession at the 4th International Converence on Vaccination which took place in Reston, Virginia.
Few authors include in descriptions the concha that Zuckerkandl described as the fourth or supreme ethmoidal turbinate. Despite some inconsistencies in Zuckerkandl s description, the concha bearing his name lies above Santorini s supreme concha, which, in turn, is above Morgagni s superior concha.
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Few other authors preferred to name Santorini s concha as the first supreme one and Zuckerkandl s concha as the second supreme one. Methods: We retrospectively documented, with various purposes, the archived cone-beam computed tomography files of patients.
Results: We found in just one case a unilateral sequence of five nasal turbinates.
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On the opposite side, only four turbinates were detected. Three-dimensional renderizations confirmed that when two supreme turbinates are found, they are joined in a common posterior tail, which, in turn, joins the tail of the superior turbinate.
Conclusions: Co-existence of two supreme conchae could either indicate their origin from different ethmoturbinals, or from the split of a commonly unique supreme one. Zuckerkandl s concha deserves therefore to be considered when anatomical descriptions, or studies, are delivered.
Systemic lupus erythematosus SLE is the prototype of connective tissue diseases that can hpv vaccine side effects denmark the complete spectrum of neurological and psychiatric dysfunctions. The precise etiological diagnosis of neuropsychiatric systemic lupus erythematosus NPSLE is rather difficult to be established and it is still controversial the exact timing of neuropsychiatric NPS events: either central nervous system CNS is the initial target of autoimmune abnormalities, either NPS symptoms are a part of multisystem involvement.
Neuroinflammation, consequent to blood-brain barrier BBB damage, local and systemic production of autoantibodies, determine neuronal injury and apoptosis, further responsible for diffuse cerebral events, mostly cognitive dysfunction and psychotic disorder.
Unguent împotriva vіdguki varicoasa Working Groups Hpv vaccine denmark Posted on februarie 8, hpv vaccine denmark comentarii De ceva ani incoace gravidele constituie o tinta pentru vaccinare, mai ales vaccinarea antigripala. Am prezentat aici prima parte dintr-un studiu ce critica recomandarea ACIP de a vaccina gravidele. Studii vaccin hpv femme prix au demonstrat absenta legaturii dintre administrarea de tiomersal si tulburarile de neurodezvoltare. Academicianul a mai spus ca Agentia Europeana pentru Evaluarea Medicamentelor Hpv vaccine hpv impfung danemark a precizat ca tiomersalul poate fi hpv impfung danemark pentru prezervarea vaccinului, daca nu exista alternativa pentru acest obiectiv. Vaccin contre papillomavirus effets secondaires Potrivit specialistului, Organizatia Mondiala a Sanatatii OMS statueaza ca nu exista dovezi stiintifice privind problemele de siguranta ale utilizarii vaccinurilor prezervate cu tiomersal si avizeaza utilizarea acestora in programele de imunizare globala, beneficiile depasind orice risc teoretic de toxicitate.
Moreover, SLE complications or therapy complications can interfere and contribute to complex clinical manifestations that can be present in SLE patients. Understanding the role of each pathogenic way can provide not only an early diagnosis, but a more accurate therapeutic approach of these patients. Toxicity and health impact of nanoparticles.
In search of new therapeutic strategies for the ischemic brain, cell-based therapies offered new hope, which has been, in the meanwhile, converted into a more realistic approach recognizing difficulties related to unfavorable environments causing low survival rates of transplanted neuronal precursors. Stem cell therapies are based on the transplantation of neuronal precursor cells NPCsadult stem cells propagated in cell culture or inducible pluripotent cells iPSCs obtained from patients and trans-differentiated into neural cells.